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Hyoung-Chun Kim Selected Research

Dextromethorphan (Racemethorphan)

12/2021Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential.
1/2011Effect of dextromethorphan on human K(v)1.3 channel activity: involvement of C-type inactivation.
10/2010Neuropsychopharmacological understanding for therapeutic application of morphinans.
1/2008Neuropsychotoxicity of abused drugs: potential of dextromethorphan and novel neuroprotective analogs of dextromethorphan with improved safety profiles in terms of abuse and neuroprotective effects.
12/20063-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.
4/2005The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan.
5/2004Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice.
1/2003Metabolism to dextrorphan is not essential for dextromethorphan's anticonvulsant activity against kainate in mice.

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Hyoung-Chun Kim Research Topics

Disease

19Cognitive Dysfunction
01/2022 - 12/2005
18Alzheimer Disease (Alzheimer's Disease)
04/2021 - 05/2004
17Mitochondrial Diseases (Mitochondrial Disease)
07/2021 - 03/2007
16Inflammation (Inflammations)
12/2020 - 05/2002
14Seizures (Absence Seizure)
01/2021 - 12/2002
13Neurodegenerative Diseases (Neurodegenerative Disease)
05/2021 - 05/2004
11Parkinson Disease (Parkinson's Disease)
07/2021 - 03/2005
11Schizophrenia (Dementia Praecox)
02/2021 - 12/2005
10Insulin Resistance
12/2020 - 01/2017
7Neuroblastoma
08/2021 - 04/2011
7Neuroinflammatory Diseases
01/2021 - 01/2009
6Memory Disorders (Memory Loss)
01/2021 - 12/2004
6Substance-Related Disorders (Drug Abuse)
11/2020 - 03/2004
6Psychotic Disorders (Schizoaffective Disorder)
04/2017 - 11/2006
5Amyloid Plaque
04/2021 - 01/2012
4Hyperthermia
08/2021 - 01/2015
4Hyperlipidemias (Hyperlipidemia)
12/2020 - 11/2014
3Neoplasms (Cancer)
01/2022 - 01/2013
3Mania (Manias)
12/2021 - 01/2020
3Type 2 Diabetes Mellitus (MODY)
09/2020 - 10/2019
3Weight Loss (Weight Reduction)
01/2018 - 09/2009
3Obesity
01/2018 - 11/2014
3Epilepsy (Aura)
08/2011 - 05/2008
2Serotonin Syndrome (Syndrome, Serotonin)
07/2021 - 01/2019
2Brain Ischemia (Cerebral Ischemia)
02/2021 - 11/2020
2Pain (Aches)
10/2019 - 09/2014
2Hypoxia (Hypoxemia)
05/2019 - 04/2019
2Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
06/2017 - 03/2014
2Necrosis
04/2016 - 01/2013

Drug/Important Bio-Agent (IBA)

19gintoninIBA
05/2021 - 01/2012
12Methamphetamine (Desoxyn)FDA LinkGeneric
07/2021 - 03/2004
12Proteins (Proteins, Gene)FDA Link
04/2021 - 05/2004
9Lysophosphatidic Acid ReceptorsIBA
05/2021 - 01/2012
9Kainic Acid (Kainate)IBA
01/2021 - 01/2003
9Phencyclidine (Angel Dust)IBA
11/2018 - 05/2004
8Dextromethorphan (Racemethorphan)FDA LinkGeneric
12/2021 - 01/2003
7Cholinergic Agents (Cholinergics)IBA
04/2021 - 06/2006
7Glutathione (Reduced Glutathione)IBA
01/2021 - 09/2011
7AntioxidantsIBA
01/2019 - 01/2004
6Cocaine (Cocaine HCl)IBA
11/2020 - 04/2016
6Neuroprotective AgentsIBA
06/2012 - 12/2006
5LigandsIBA
04/2021 - 01/2012
5PalmitatesIBA
12/2020 - 01/2017
4trimethyltinIBA
08/2021 - 08/2011
4Lipoxygenase (Lipoxygenase-1)IBA
08/2021 - 01/2017
4Dopamine (Intropin)FDA LinkGeneric
08/2021 - 03/2007
4ginsenoside ReIBA
07/2021 - 06/2014
4lysophosphatidic acidIBA
05/2021 - 12/2016
4Small Interfering RNA (siRNA)IBA
12/2020 - 01/2018
4N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
05/2020 - 12/2005
4Insulin (Novolin)FDA Link
03/2020 - 09/2014
4Interleukin-6 (Interleukin 6)IBA
11/2019 - 06/2013
410,17- dihydroxydocosa- 4,7,11,13,15,19- hexaenoic acidIBA
10/2019 - 01/2017
4Protein Kinases (Protein Kinase)IBA
01/2018 - 05/2002
4Reactive Oxygen Species (Oxygen Radicals)IBA
07/2015 - 05/2004
3CytokinesIBA
08/2021 - 05/2002
3DNA (Deoxyribonucleic Acid)IBA
08/2021 - 01/2004
3Glutathione PeroxidaseIBA
07/2021 - 05/2008
3Serotonin (5 Hydroxytryptamine)IBA
07/2021 - 03/2010
3EnzymesIBA
02/2021 - 10/2015
3GinsenosidesIBA
05/2020 - 01/2009
3AMP-Activated Protein KinasesIBA
10/2019 - 01/2017
3Morphine (MS Contin)FDA LinkGeneric
12/2018 - 09/2014
3NADPH Oxidases (NAD(P)H oxidase)IBA
11/2018 - 01/2016
3Fatty Acids (Saturated Fatty Acids)IBA
10/2018 - 01/2017
3Phosphatidylcholines (Phosphatidylcholine)IBA
01/2018 - 11/2014
3Docosahexaenoic AcidsIBA
01/2018 - 01/2017
3LipidsIBA
01/2018 - 11/2014
3Amyloid (Amyloid Fibrils)IBA
12/2016 - 08/2015
3Naloxone (Narcan)FDA LinkGeneric
10/2016 - 09/2009
3Caspase 3 (Caspase-3)IBA
04/2016 - 03/2012
3Growth Hormone (Somatotropin)IBA
09/2014 - 09/2005
3Amyloid beta-PeptidesIBA
09/2013 - 12/2004
3LipopolysaccharidesIBA
01/2010 - 12/2006
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2021 - 01/2019
25-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
07/2021 - 07/2009
2Neurotransmitter Agents (Neurotransmitter)IBA
02/2021 - 01/2020
2SeleniumIBA
02/2021 - 12/2020
2Pharmaceutical PreparationsIBA
02/2021 - 03/2014
2Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2021 - 12/2018
2ginsenoside Rg3IBA
05/2020 - 03/2014
2LithiumIBA
02/2020 - 01/2020
2Dextroamphetamine (Dexedrine)FDA LinkGeneric
02/2020 - 01/2020
2Superoxide DismutaseIBA
02/2020 - 05/2008
2Glucose (Dextrose)FDA LinkGeneric
11/2019 - 01/2017
2Janus Kinase 2IBA
01/2019 - 11/2017
24- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
11/2018 - 01/2016
2Clozapine (Clozaril)FDA LinkGeneric
11/2018 - 05/2018
2Trichloroethylene (Trichloroethene)IBA
07/2018 - 02/2010
2Antipsychotic Agents (Antipsychotics)IBA
05/2018 - 12/2005
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2018 - 01/2017
2DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
01/2018 - 08/2015
2JNK Mitogen-Activated Protein KinasesIBA
01/2018 - 01/2018
2prolinedithiocarbamate (PDTC)IBA
01/2018 - 05/2004
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2017 - 06/2013
2NicotineFDA Link
06/2017 - 03/2007

Therapy/Procedure

8Oral Administration
04/2021 - 11/2009
4Therapeutics
10/2019 - 03/2005
2Steam Bath (Sauna)
09/2020 - 10/2019
2Self Administration (Administration, Self)
01/2019 - 12/2018